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Welcome to Active Bodies, Active Minds. This week, we consider the physical function of older adults, from fall prevention programs for older Black people and environmental fall risks to remote assessments and biological markers of performance. We also examine the nervous system, with a look at how medication affects motor nerves in people with PD and what structural changes in the brain reveal about dementia. Finally, this issue explores how health concepts take shape, both in the formation of personal beliefs about chronic pain and in the development of a framework for nature prescribing.
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What makes a fall prevention program appealing to older Black people?
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Participation among older Black people in community-based fall prevention exercise programs remains low, and there is a lack of research on their specific needs and perspectives. To explore this issue, this study used semi-structured interviews with a sample of 23 Black people aged 50 and older.
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Lochan-Aristide, M., Bouchard, D. R., & Dogra, S. (2026). The Lived-Experiences and Recommendations of Older Black Canadians regarding Community-Based Fall Prevention Exercise Programs: A Qualitative Study. The Gerontologist. https://doi.org/10.1093/geront/gnag051
Shilpa Dogra
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Does medication for dopamine loss restore normal motor nerve firing?
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In Parkinson’s disease, the degeneration of dopaminergic neurons disrupts motor function and may also alter motoneuron excitability. This study investigated motoneuron excitability in people with PD, during both ON and OFF medication states, and compared these responses with controls of a similar age.
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Alaei, P., Pearcey, G. E., Wile, D. J., Holobar, A., & Jakobi, J. M. (2026). Motoneuron Excitability in Parkinson’s Disease: Effects of Dopaminergic Medication. Journal of Neurophysiology. https://doi.org/10.1152/jn.00614.2025
Jennifer Jakobi
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Can chemical marks on your DNA reflect your body's physical performance?
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Detecting the subtle physical decline that can begin in midlife is a challenge for promoting healthy aging. This study examined the feasibility of using DNA-based biological age estimators as markers for physical performance in adults aged 39 years and older.
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Insler, M., Shapiro, M., Hermush, V., Kopelman, N. M., Atzmon, G., & Springer, S. (2026). Epigenetics as Biomarkers of Cumulative Physical Performance in Community-Dwelling Adults: A Cross-Sectional Feasibility Study. Cells, 15(8), 718. https://doi.org/10.3390/cells15080718
Shmuel Springer
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How can physical function in older adults be assessed and managed remotely?
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This research addresses the implementation of remote care approaches for assessing and managing physical function in older adults. To do so, the study utilized a Delphi process.
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Via, J. D., Hurst, C., Dent, E., Fyfe, J. J., Jansons, P., Hayes, E. J., Sim, M., Aubertin-Leheudre, M., de Lima, A. B., Bohn, L., Britting, S., Buckinx, F., Connolly, G., Giangregorio, L., Henriques-Neto, D., Jones, J. R., Kob, R., Morin, S. N., N, G., ... Orssatto, L. B. (2026). Remote assessment and management of physical function in older adults (RAMP): An international expert Delphi process. Archives of Gerontology and Geriatrics, 147, 106266. https://doi.org/10.1016/j.archger.2026.106266
Lora Giangregorio
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What does a standard for prescribing nature require?
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Although healthcare providers can recommend nature exposure for health benefits, there is no shared definition or framework to guide the use of these nature prescriptions. To address this, researchers used a multi-round consensus process involving focus groups and surveys with an international panel of experts to develop a guiding framework.
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Struthers, N. A., Zecevic, A. A., Stanhope, J., Breed, M. F., Gittings, L., Gunz, A., Wagenfeld, A., Birmingham, T., Kothari, A., & Maric, F. (2026). An international and interdisciplinary framework for nature prescribing in healthcare: A modified Delphi study. PLOS Global Public Health, 6(4), e0006361. https://doi.org/10.1371/journal.pgph.0006361
Anita Kothari
Aleksandra A. Zecevic
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Where do our beliefs about chronic pain come from?
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The sources of information and the mechanisms individuals use to form their beliefs about chronic musculoskeletal pain are not well understood. To address this, researchers recruited adults with the condition from the general public and undertook a multi-stage data analysis to identify themes about how these beliefs are constructed.
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Dunn, M., Rushton, A. B., Heneghan, N. R., & Soundy, A. (2026). How individuals formulate their beliefs about chronic musculoskeletal pain: introducing the dual implicit-explicit processing (DIP) model of pain belief formation — a qualitative exploration. BMC Musculoskeletal Disorders. https://doi.org/10.1186/s12891-026-09835-5
Alison Rushton
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What do changes to the surface of the hippocampus show about disease progression that its loss of volume does not?
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While the hippocampus area of the brain is known to shrink in Alzheimer's disease, other changes to its surface shape are not as well understood. To investigate these changes, researchers analyzed MRI data from hundreds of individuals, tracking the volume, curvature, gyrification, and thickness of hippocampal subfields over time.
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Aziz, S., Penheiro, R., Morrison, C., Zhukovsky, P., & Anderson, J. A. (2026). Longitudinal Surface-Based Morphometry Changes in the Hippocampus in Dementia. Neuropsychologia, 109470. https://doi.org/10.1016/j.neuropsychologia.2026.109470
John Anderson
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Canadian Centre for Activity and Aging
Faculty of Health Sciences, Western University
1201 Western Road Elborn College, Suite 1101, London, Ontario N6G 1H1, CA
ccaa@uwo.ca
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Some components of this newsletter were generated using AI.
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